If you are a molecular modeler, you are likely all too familiar with the challenge of efficiently navigating and managing molecular sequences alongside their 3D structures. Switching back and forth between sequence information and structural representations can slow down workflows. SAMSON offers a practical solution: the Sequence View. This feature bridges the gap between your molecular sequence and its structure, allowing seamless and synchronized interaction between views.
Why Sequence View Can Help
Using the Sequence View in SAMSON, you can simultaneously visualize and work with molecular sequences and structures. Imagine selecting a residue in the sequence and instantly seeing it highlighted in both the Document View and the 3D Viewport. This synchronization minimizes errors and ensures efficiency. It’s an essential tool for researchers who need to cross-reference sequences with 3D conformations.
But that’s not all. The Sequence View also lets you colorize residues based on their biophysical properties. This means you can quickly gain insights into the molecular model, as these color classifications can also propagate to the 3D Viewport, making structural hotspots easier to visualize and analyze.
Ways to Access the Sequence View
Accessing the Sequence View in SAMSON is straightforward and flexible. Here are two simple methods:
- Click the View sequence option from the Home menu:

- Alternatively, right-click on a structure, and from the Context menu, select Structural model > View sequence:

If your molecular structure contains multiple chains, don’t worry! A convenient pop-up will appear, allowing you to choose which sequence(s) you would like to view:

Quick Visualization with Biophysical Colorization
A standout feature of the Sequence View is its ability to colorize residues based on biophysical properties. This colorization makes it easy to assess various molecular properties directly at a glance. Once applied to the sequence, the selected color coding instantly appears in the 3D Viewport, enabling unparalleled clarity in understanding structural biophysical characteristics.

Optimize Your Molecular Workflow
The benefits of the Sequence View extend far beyond convenience. By syncing the sequence and structure and simplifying color-coded visualization, it empowers molecular modelers to focus on meaningful analysis rather than tedious setup. This feature reduces errors, improves visualization clarity, and supports more informed decision-making in molecular design projects.
For an overview of the Sequence View and to explore its full range of features, visit the original documentation at https://documentation.samson-connect.net/users/latest/sequence-view/.
Note: SAMSON and all SAMSON Extensions are free for non-commercial use. Download SAMSON today at https://www.samson-connect.net.
