For molecular modelers, selecting specific residues and structures within complex models can be a frequent yet cumbersome task. The more intricate the molecule, the more tedious manual searching and selecting becomes. This is where the Sequence View in SAMSON shines, offering an interactive and efficient solution to streamline molecular selection and visualization workflows.
What is the Sequence View?
The Sequence View is an intuitive, interactive interface provided by SAMSON that synchronizes seamlessly with the Document View and the 3D Viewport. In practice, this means that residues selected in the Sequence View are automatically highlighted in the 3D Viewport and vice versa. This bi-directional synchronization eliminates guesswork and enables faster, more accurate residue selection within complex molecular systems.

Effortless Colorization for Better Insight
But the Sequence View does more than just selection. One of its standout features is the ability to colorize residues within the sequence to reflect intricate biophysical properties. For instance, you can assign colors to residues based on properties like charge, hydrophobicity, or custom-defined schemes relevant to your research. These colors are transferred directly to the 3D viewport, providing an immediate visual cue to understand structural and functional relationships.

How to Access Sequence Views
Accessing the Sequence View is straightforward. You can initiate it in two ways:
- By clicking on the View sequence command within the Home menu. Here is how it looks:

- By right-clicking on a structure and selecting Structural model > View sequence from the Context menu:

If the structure you’re working on contains multiple chains, a convenient pop-up will appear, allowing you to choose which chain(s) you would like to view. This makes tackling large macromolecules, like proteins with multiple domains, much simpler.

Make Model Building More Intuitive
Ultimately, SAMSON’s Sequence View removes many frustrations from molecular modeling by simplifying residue interactions, enabling insightful colorization, and effortlessly linking sequences to the 3D structural models you’re designing or analyzing. If you haven’t explored this feature yet, it’s time to see how it can save you time and deliver precision to your projects.
For more detailed information and step-by-step instructions, visit the official documentation page on Sequence Views.
SAMSON and all SAMSON Extensions are free for non-commercial use. Start your molecular modeling journey today by downloading SAMSON at samson-connect.net.
