Modern High DPI monitors are a game-changer for molecular modeling. Crisp visuals and detailed displays can truly elevate your design experience, but they also come with occasional quirks. Many SAMSON users working on High DPI monitors have encountered a common issue: the icons in the application appear too small, making it challenging to navigate efficiently. If you’re facing this, worry not! This blog post will guide you step-by-step to solve the issue on Windows systems.
Understanding the Issue
Applications designed before High DPI displays became mainstream may not scale seamlessly on modern high-resolution monitors. This results in UI components like icons appearing disproportionately small, even if the rest of the content is appropriately scaled. If you’ve experienced this in SAMSON, the solution lies in tweaking system compatibility settings.
Step-by-Step Solution
Adjusting Compatibility Settings
Here’s how you can make SAMSON icons larger on a Windows High DPI monitor:
- Locate the SAMSON Executable: Navigate to the folder where your SAMSON executable is located, right-click the program, and select Properties.

- Open the Compatibility Tab: In the Properties window, access the Compatibility tab. Under this section, you’ll find options dedicated to handling DPI settings.
- Change High DPI Settings: Click the button labeled Change high DPI settings. Next, check the box for Override high DPI scaling behavior.
- Set Scaling Option to ‘System’: From the drop-down menu, select System for the scaling behavior. This setting ensures that the operating system manages scaling, making icons larger and clearer.

- Restart the Application: Once the settings are saved, restart SAMSON. You should now notice significantly improved icon scaling that enhances usability.
When to Use This Solution
This method works best for users experiencing scaling issues on Windows systems. For macOS or Linux users, or if you’re experiencing different UI-related concerns, consider exploring the SAMSON Troubleshooting Guide for relevant solutions.
Your Feedback Matters
We encourage users to share their experiences in the SAMSON Connect Forum, especially if you’ve encountered notable quirks on unconventional setups. The community thrives on collaboration, and your feedback could help improve the platform even further.
For more detailed guidance on troubleshooting SAMSON for various use cases, visit the official documentation page: SAMSON Troubleshooting.
Note: SAMSON and all SAMSON Extensions are free for non-commercial use. Download SAMSON today at SAMSON Connect.
