A Closer Look: How Ambient Occlusion Can Improve Molecular Visualizations

Communicating molecular structures effectively isn’t just about showing atoms and bonds — it’s about delivering clarity. For molecular modelers, one persistent challenge is depth perception: distinguishing foreground and background parts in complex 3D structures. If you’ve ever struggled with interpreting or presenting a dense protein or molecule visualization, you already know how important depth cues are.

This is where Ambient Occlusion in SAMSON can make a difference. Ambient occlusion is a rendering technique that simulates how light is blocked by surrounding geometry, making deeper regions appear darker. The result? A visual cue that immediately enhances your perception of structure depth.

Two Options for Different Situations

SAMSON offers two types of ambient occlusion, each suitable for different needs:

  • Screen-space Ambient Occlusion (SSAO): Fast and efficient, SSAO is great for real-time adjustments. The effect varies slightly with the camera’s distance but greatly improves depth perception even on large systems.
  • Object-space Ambient Occlusion: This provides a more realistic shadowing effect but is computationally more intensive. Use it when quality trumps speed — for example, in final rendering or publication figures.

Here’s a visual comparison using the Ribbon representation of the 1AF6 molecule. First, without any ambient occlusion:

No ambient occlusion

Now, with screen-space ambient occlusion turned on:

With ambient occlusion

Notice how the added shadows give structure to the protein, helping the viewer immediately identify folds and cavities? This small adjustment makes a big impact in both exploratory modeling and clear presentations.

How to Enable It

There are two simple ways to start using ambient occlusion in SAMSON:

  • For fast toggling, go to Visualization > Options and switch it on or off instantly.
  • For deeper customization, head to Preferences > Rendering > Ambient Occlusion. Here you can tweak the strength, radius, and other parameters to suit your visualization style.

The ambient occlusion settings

When Should You Use It?

Ambient occlusion is incredibly helpful in situations where:

  • You’re building presentations or figures that need to be visually digestible at a glance
  • You’re trying to make clear distinctions between nested structures, binding pockets, or molecular surfaces
  • Your model is complex and hard to read without added depth

Even for standard structure exploration, enabling SSAO while you work can change how you perceive your model — catching details that are often lost in flatter renderings.

To summarize, ambient occlusion is a small switch with a big payoff. If you’ve been manually adjusting lighting or struggling to “see” shapes properly in your molecular models, take a minute to try this feature in SAMSON. It might just become a default in your workflow.

To learn more about all rendering effects available in SAMSON, visit the full documentation here: https://documentation.samson-connect.net/users/latest/rendering-effects/

SAMSON and all SAMSON Extensions are free for non-commercial use. You can download SAMSON at https://www.samson-connect.net

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