Installing a new software platform can be an intimidating process, especially in the world of molecular modeling where specialized requirements often come into play. For those eager to dive into computational nanoscience and take advantage of SAMSON’s capabilities, we’ve broken down the installation process to ensure a smoother experience.
Why Prepare for SAMSON Installation?
SAMSON is a powerful tool for molecular design, offering integrative solutions across disciplines such as life science, material science, and chemistry. But before you start using its features, it’s essential to ensure your operating system and hardware meet SAMSON’s requirements to make the installation seamless. For example, SAMSON supports Windows 10 and 11, Linux distributions like Ubuntu 22.04 or newer, and macOS 12 (Monterey) and later versions. You’ll also need a 64-bit operating system with a graphics card supporting OpenGL 4.1.
Let’s explore the steps together for each platform.
Getting Started
To install SAMSON, the first step is to download the SAMSON installer from SAMSON Connect. You will need to either sign into your account or create one if you don’t already have one. During the installation, you’ll provide the email address you used for registration and your SAMSON key, which is accessible through your account settings or the download page.
Below, we outline the simple steps required for installation on different systems.
Installing on Windows
Once you download the installer, simply run it to launch the installation process. Confirm the license agreement and follow the prompts. The installer automatically checks your system for access to SAMSON Connect for downloading necessary modules.
If no issues are detected, SAMSON will complete the installation and display a confirmation screen allowing you to start SAMSON or visit SAMSON Connect directly.

Installing on macOS
Mac users will find the process equally simple. After downloading the installer, run it from your launchpad or Applications folder. Note that you might need to provide full disk access for SAMSON. For more details about this post-installation step, refer to the Full Disk Access on macOS section in the official documentation.
Installing on Linux
On Linux, you will need to make the installer executable and follow a few additional steps via the terminal:
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cd ~/Downloads<br>chmod +x ./SAMSON-Setup.run<br>QT_QPA_PLATFORM=xcb ./SAMSON-Setup.run |
Linux users may also need to install some dependencies for the software to run smoothly. For instance, on Ubuntu, you’ll typically require libraries like libxcb-cursor0 and libatomic1. Execute the following command to install them:
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sudo apt install libxcb-cursor0 libatomic1 |
For CentOS-like systems, the xcb-util* packages are recommended:
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sudo dnf install xcb-util* |
What Happens Next?
Once the installation is complete, SAMSON allows you to start working right away. By default, the platform downloads a set of essential extensions, but you can easily customize your setup with additional modules from the Marketplace.
Final Notes
Installing SAMSON doesn’t require admin rights, which means the software installs itself in your user directory and ensures minimal disruption to system privileges. It’s also worth noting that SAMSON is updated regularly, so make sure to upgrade to the latest version whenever available for optimal performance and to access newly developed features.
For more detailed information, refer to the installation section on the official documentation at this link.
Note: SAMSON and all SAMSON Extensions are free for non-commercial use. Download SAMSON today at https://www.samson-connect.net.
