When working on complex molecular systems, even small time savings can improve focus and productivity. If you’re navigating through menus repeatedly in SAMSON, there’s a quicker way to access your assistant: keyboard shortcuts. SAMSON AI, the intelligent assistant powered by GPT-5 (available in the Professional plan), is only a shortcut away — and it can help you execute advanced modeling actions without switching to the mouse.
Instant Access to SAMSON AI
Instead of clicking through the menu (Interface > Assistant), you can summon SAMSON AI in seconds using this shortcut:
- Windows & Linux: Ctrl + 0
- macOS: Cmd + 0
This small detail might seem simple, but frequent users will save clicks and seconds every time they want to chat or launch a command with SAMSON AI.
What Can You Do Once You’re There?
Once the Assistant is open, typing / reveals a list of available commands. These allow you to:
/do: Perform direct actions like zooming, coloring, or removing water molecules./script: Generate Python scripts for repetitive or advanced tasks./select: Use natural language to select molecular nodes./learnand/refer: Instruct SAMSON AI to read documents and answer scientific questions about them./forget: Clear learned content from memory.
This means you can jump straight into scripting or data queries with just a couple of keystrokes.
Example Flow: From Shortcut to Script
Here’s one speed-enhancing use case:
- Press Ctrl + 0 (or Cmd + 0) to activate SAMSON AI.
- Type
/script compute the gyration radius of the receptor. - Paste or modify the generated Python script as needed, or just run it.
Everything happens in place — no window jumping, no scripting tutorials required.
Visual Overview of Commands

The Assistant also suggests prompts and alternatives when you start typing /, making the learning curve gentler for new users.
Why It Matters
Molecular modeling is often an iterative and exploratory process. Reducing the friction between your thought process and execution — whether it’s selecting atoms within 5 Å of a ligand, or iterating over visualization models — helps keep you in the zone.
Using one simple shortcut, you’re not just launching a tool. You’re transitioning into a space where data, visuals, and AI-driven decisions become seamlessly accessible.
Learn more about SAMSON AI and explore all available assistant commands.
SAMSON and all SAMSON Extensions are free for non-commercial use. You can download SAMSON at https://www.samson-connect.net.
