For molecular modelers, managing the complex relationship between sequences and 3D structures is a daily challenge. Whether you’re diving into structural details, analyzing residues, or preparing visualizations, the ability to synchronize sequence data with the corresponding 3D model can significantly streamline workflows. This is where SAMSON’s Sequence View comes into play, offering a feature-packed, synchronized approach to interact with molecular sequences.
What is the Sequence View?
The Sequence View in SAMSON is a dynamic tool that links sequence representations and the 3D Viewport. It empowers you to:
- Select residues: Any selection you make in the Sequence View is automatically reflected in the Document View and 3D Viewport, and vice versa.
- Colorize residues: You can highlight residues based on their biophysical properties and apply those colors directly to 3D structures.
This synchronization ensures that molecular modelers save time and reduce errors while maximizing their productivity during structural analysis.
Accessing the Sequence View
Getting started with the Sequence View is simple. SAMSON offers two easy methods:
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From the Home menu: Click on the View sequence command to open the Sequence View for your structure.
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From the Context menu: Right-click on a structure, navigate to Structural model > View sequence, and select it.
If you’re working with multi-chain structures, a pop-up dialog will let you choose which sequence(s) to view. This ensures clarity and control over your workflow:

Enhanced Colorization
One of the standout features of Sequence View is its ability to transfer colorization to 3D structures. This is particularly useful for visualizing biophysical properties in an intuitive way. Whether you need to emphasize hydrophobic regions, charge distributions, or other characteristics, the intuitive interface of SAMSON makes this process seamless:

Why Use the Sequence View?
Here are key reasons why Sequence View is a must-have tool for molecular modelers:
- Time-saving selection: With synchronized views, you can effortlessly navigate between sequence data and 3D models.
- Enhanced communication: Color-coded residues ensure your visualizations are easy to interpret for collaborators.
- Streamlined workflows: Quickly transition from analyzing sequences to working with their 3D counterparts.
Learn More
The Sequence View is an indispensable tool for molecular modelers looking to simplify structure-sequence interactions while improving visualization quality. To explore more about the Sequence View, check out the official SAMSON documentation at https://documentation.samson-connect.net/users/latest/sequence-view/.
SAMSON and all SAMSON Extensions are free for non-commercial use. You can download SAMSON at https://www.samson-connect.net.
