For molecular modelers diving into umbrella sampling workflows, deriving the Potential of Mean Force (PMF) profile is often a pivotal step that can reveal critical insights into reaction mechanisms, binding affinities, and more. However, this phase can pose challenges, especially…

Animating molecular interactions is a critical task for molecular modelers. Whether you’re visualizing docking processes, creating dynamic presentations of molecular assemblies, or showcasing molecular motions, animations help bring molecular models to life. To solve this common need, SAMSON provides a…

For molecular modelers, understanding large-scale biomolecular motions such as binding-site openings or protein conformational changes is often critical. However, performing such analyses can be challenging without the right tools. This is where SAMSON’s Normal Modes Advanced (NMA) extension provides an…

When working on protein modeling, one of the persistent challenges is ensuring that the conformations of amino acid residues are energetically favorable. The Ramachandran Plot has long been a core element in this process, giving molecular modelers a visual representation…

As a molecular modeler, you know how important it is to have the right tools for the job. Whether it’s visualizing proteins, analyzing molecular interactions, or preparing drug candidates, each task requires specialized tools that can be time-consuming to manage.…

Are you using SAMSON on a high DPI monitor and noticing that the icons appear unusually small? This can be frustrating, especially during long molecular modeling sessions where clear visuals make a big difference in productivity. If you’re using Windows,…