When exploring ligand unbinding pathways in molecular modeling, precision is crucial. One particular challenge molecular modelers often face is defining the sampling region effectively to yield meaningful and accurate pathways. The sampling box, as defined in the SAMSON documentation for…

Minimizing molecular structures is a fundamental task in molecular modeling. But what if you're dealing with a large molecule and only need to optimize part of it without affecting the rest? SAMSON, the integrative molecular design platform, provides an intuitive…

For molecular modelers, visualizing intricate nanosystems effectively is a crucial part of their workflows. Whether you’re examining protein secondary structures, electron density maps, or electrostatic fields, a clear and intuitive graphical representation can make a world of difference. SAMSON, the…

Molecular modelers often face the challenge of designing intricate shapes at the nanoscale with precision and flexibility. While molecular structures are fascinating in themselves, finding tools that allow creative and efficient manipulation can be a game-changer. Enter the SAMSON platform’s…

If you’re a molecular modeler, you’ve likely encountered the need for precise reproducibility or compatibility with specific software versions. When working with GROMACS Wizard on SAMSON, you’re in luck: it allows you to use a custom version of GROMACS instead…

For molecular modelers, achieving an effective and clear visualization of a complex molecular system is frequently a challenge. Whether you are presenting results to a group of researchers, preparing insights for a paper, or simply analyzing molecular interactions, getting the…

When working on molecular models, there are times when you need to focus on certain elements while temporarily hiding others. Adjusting these visibilities manually across different frames can be time-consuming and prone to errors. The Hidden animation in SAMSON provides…

Center-of-mass (COM) pulling simulations are an essential tool for molecular modelers aiming to explore interactions or dissociations between molecular systems. Traditionally, setting up such simulations can be quite intricate, requiring careful attention to system preparation, box dimensions, and pulling parameters.…

For anyone tackling molecular modeling challenges, creating custom polymers with precise structural requirements can be a daunting task. That’s where SAMSON’s Polymer Builder Extension steps in — offering the ability to design flexible, complex polymers from scratch using custom monomers.…